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Ashley McEnery shared thisAnna Marie Wagner So excited to have you join. Looking forward to seeing everyone at UnlockAshley McEnery shared thisAnna Marie Wagner is joining UNLOCK 2026. A lot of what scientists learn in the lab gets buried in notes, lost in handoffs, or stuck in one person's head. Transfyr is working on fixing that. Anna Marie is Co-Founder and CEO at Transfyr, where she's building AI-powered infrastructure to make scientific knowledge more transferable and reproducible. Hear it from her directly at UNLOCK. April 22. San Francisco. unlockscience.ai
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Ashley McEnery shared thisFor those outside of biotech, Aviv Regev is one of the most important voices in the field. She’s helped define the intersection of biology, computation, and drug discovery. Excited to see her keynote UNLOCK 2026.Ashley McEnery shared thisWe are thrilled to announce Aviv Regev as the keynote speaker for UNLOCK 2026. Aviv is widely considered one of the most influential scientists working today. Currently Executive Vice President and Head of Research & Early Development at Genentech, she's leading the integration of biology and AI to transform drug discovery. Having held senior leadership roles at the Broad Institute of MIT and Harvard and won numerous prizes and accolades, her experience is second to none. As one of the most pioneering minds in biotech, there's no one better to speak to where we're all going. UNLOCK 2026 · April 22 · San Francisco Request an invite → https://unlockscience.ai
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Ashley McEnery posted thisI'm joining Medra to lead Finance & Ops. This is a long time coming. Over the past year, I've become convinced that AI disconnected from the physical world leaves the hardest problems unsolved. Real impact requires closing the loop between intelligence and execution. That's what brought me to Medra. Medra is building Physical AI Scientists that pair computational intelligence with real-world experimental throughput. This spring, we're opening ML01, one of the largest autonomous labs in the United States, running experiments 24/7 to generate the data infrastructure biology needs. I've spent my career building operational foundations at critical inflection points. At Xbox, I helped to drive the shift to community and subscriptions. At Discord, I built the subscription strategy that scaled the platform from free service to >$100M revenue. At Vercel, I worked to transform the company from open-source community to frontend and infrastructure juggernaut, building the foundation that scaled it from $10M to >$100M revenue. Now I’m joining Michelle Lee on the hardest and most important challenge - to eradicate disease. If you’re in SF, come over and see what we’re cooking in the lab. (Also, we’re hiring!)
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Ashley McEnery reposted thisAshley McEnery reposted thisSomething new is coming. Human computing. A shift in how we connect with AI... and who’s on the other side. The next chapter starts soon 👉 tavus.io A countdown has begun. 7 days.
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Ashley McEnery posted thisAfter an incredible year at Pika, I'm stepping into my next adventure. Being COO has been a privilege. From the moment I met Demi, I was inspired by her vision for social-first AI. Since joining, I’ve had the chance to work alongside some of the smartest people in the industry who combine deep technical expertise with a true passion for creativity. Video is at the frontier of AI - dealing with complex questions (inference efficiency, scaling economics, open- vs closed-source dynamics, model realism, safety) while also integrating all of it into an end-to-end product experience. I’m excited for everyone to see what the team is cooking, and grateful to have been part of this journey. I will continue to be a core user and cheerleader. Special thanks to Demi G., Chenlin Meng, Matan Cohen Grumi — and to the rest of the amazing Pika team for their partnership and trust. Looking forward to sharing what's next for me!
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Ashley McEnery reposted thisAshley McEnery reposted thisEverything sucks, but it’s not the end of the world—because with Pika, reality is optional. Deflate what you hate. Turn turds into treasure. Make hazmat high fashion. If we’re doomed…let’s at least have a little fun with it. #Pikapocalypse
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Ashley McEnery shared thisIncredibly proud of Pika for being included on Fast Company's Most Innovative Companies in Applied AI! Huge kudos to Demi G. Chenlin Meng and the entire Pika crew. Love seeing what's possible with a small, execution-focused team - and excited to be a part of itThe most innovative companies in applied AI for 2025The most innovative companies in applied AI for 2025
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Ashley McEnery shared thisExcited to announce the latest innovation in AI Video - Pikadditions! This is the first time users can combine real-world videos and images. Huge kudos to the team on this advancement. This was so much fun to work on. Now on to the next ship.Ashley McEnery shared thisSurprise! Today, we’re launching Pikadditions, the easiest way to make your content stand out. Add anyone or anything to any video, whether that’s a video you shoot yourself, or a favorite clip. New users get fifteen free Pikadditions generations when they sign up. Go try it at pika dot art
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Ashley McEnery shared thisBusiness model innovations are always my favorite types of launches.Ashley McEnery shared thisIt’s go time 🏁🔥 Introducing Turbo Mode: Make more for less. Generate mind-blowing AI videos 3x faster, for 7x fewer credits, without compromising on quality. Ready, set… Go try it at pika dot art
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Ashley McEnery liked thisAshley McEnery liked thisMost people using AI in drug discovery are running on hype. Ron and the NOETIK team are curing cancer. Announcing Ron Alfa, MD, PhD, Co-Founder and CEO of Noetik, as a speaker at UNLOCK 2026. Noetik was founded to answer the question that's frustrated him since medical school: why, with everything we know about biology, don't we have better cancer drugs? The answer is that the field has been building on the wrong data. Noetik trains virtual cell foundation models on the largest spatial biology dataset in oncology, simulating tumor-immune interactions at a resolution that changes what questions you can even ask. GSK agreed, to the tune of $50M. Find out more at UNLOCK 2026. April 22 · San Francisco Register at https://unlockscience.ai
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Ashley McEnery liked thisIncredibly excited to welcome Mitchell to the Vercel Board of Directors. He's a developer's developer who deeply believes in open source, and who's built both foundational infrastructure for the internet, and a generational company. LFGAshley McEnery liked thisExcited to share that I've joined Vercel's Board of Directors. Vercel is made up of builders and tastemakers that continually ship things that deeply impact how developers work: Next.js, AI SDK, v0, etc. I can't think of a more exciting place to be. Let's fucking ship. ▲ My relationship with Vercel goes back to the earliest days. HashiCorp was an early adopter of NextJS and Vercel (~10 years ago!) and it remains my default tech stack and deployment platform to this day. Ghostty's website is all on Vercel, too! Beyond that, I've been continually impressed with the teams relentless focus on shipping meaningful software. And importantly, software that has incredible taste. Now we are in the age of agentic software development. Vercel is building agentic infrastructure that I think every app and agent will need (I certainly need it!) and I can't think of a more exciting place to be. Huge thanks to Guillermo Rauch , Jeanne DeWitt Grosser, Marten Abrahamsen, Malte Ubl, Tom Occhino and the entire Vercel team for the warm welcome. Time to work.
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Ashley McEnery liked thisAshley McEnery liked thisWe’re welcoming Mitchell Hashimoto to the Vercel board of directors today. Mitchell has impacted how developers build and operate software at every layer of the stack. He co-founded HashiCorp and created Terraform, establishing the standard for infrastructure-as-code. After growing the company to a multi-billion dollar outcome, he stepped right back into founder mode with Ghostty. We are honored to add his open source leadership and engineering expertise to our board. Welcome, Mitchell! https://lnkd.in/g6cR4MrrVercel Appoints Mitchell Hashimoto, Co-Founder of HashiCorp and Creator of Terraform, to Board of DirectorsVercel Appoints Mitchell Hashimoto, Co-Founder of HashiCorp and Creator of Terraform, to Board of Directors
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Ashley McEnery reacted on thisAshley McEnery reacted on thisEarlier this year, I left my role as President & COO at Mux after 7.5 years. It was an incredible journey with an amazing team. Thank you Jon Dahl, Steve Heffernan, Matthew McClure and Adam Brown for the chance to build Mux alongside you for so many years! In this next chapter, I’m excited to advise, invest and explore before jumping into the next venture. This week I started that chapter with a couple new roles to share. I’m joining the Board of Directors at Mux to continue steering our vision to build video for developers. It’s an exciting time for Mux (lots of growth, new products launching, hiring), and I’m excited to work alongside Jon and the board in a different role. I’m also joining the great folks at Accel as an Executive-in-Residence to advise portfolio companies and learn from some of the smartest investors and operators I’ve ever met. Thanks Vas Natarajan and Dan Levine for the opportunity! If I can be helpful to you in this next chapter, I’d love to hear from you!
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Ashley McEnery reacted on thisAshley McEnery reacted on thisWrapping up my first week at Medra today! I'm enjoying this shift into biotech and the opportunity to work on a new set of impactful problems. There's momentum on the team, and it's been fun to jump right in. Medra is building systems that can run real lab experiments end-to-end using robotics and AI, then use the results to improve the next iteration. The goal is to run more experiments, learn faster, and speed up drug discovery. Coming from vehicle autonomy, what drew me here was a familiar challenge underneath a new domain: building systems that close the loop between physical action and learning. Different industry, same core obsession. Before this, I spent almost 4 years at Applied Intuition working on offroad vehicle autonomy. Grateful for everything I learned there, and excited to see what the team builds next.
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Daniel Dart
Rock Yard Ventures • 10K followers
🚨NEW EPISODE: Recorded live at FUTURE TITANS 2026 - Jeff Perry of Carta sat down with the iconic Seth Levine, co-founder of Foundry. Seth has been in venture for 25 years, built Foundry from scratch as an emerging manager himself, and has backed about 50 emerging manager funds through his fund of funds. He has genuinely seen every side of this table. They went deep on building Foundry, why VCs are in the influence business, not the decision business, and why the concentration problem in venture is not only bad for LPs, but also for the innovation ecosystem overall. And why Seth's new book, Capital Evolution, is so important for the future of America. 🎧 Links to listen... Apple: https://lnkd.in/ehQUQ2EM Spotify: https://lnkd.in/eU4FExpg
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Lakshmi Shankar
Together • 3K followers
Thrilled to announce that Together Fund is investing in Sentra, alongside a16z speedrun! You track results in Jira. Decisions in Notion. Conversations in Slack. But the reasoning, the debates, trade-offs, and context behind why you chose A over B, disappears into what we call "Dark Matter." A decision made in March looks insane by July because no one remembers the constraints that made it smart. I lived this firsthand at Twitter scaling from 800 to 8,000 employees, and at Google while launching AI Overviews to billions at planet scale. The problem isn't process. Process is compensation for something deeper: organizational amnesia. An organization’s "Systems of Record" doesn’t solve this, they encode it. They store what happened, never why. That's why we are investing in Sentra. Sentra is the always-on collective memory that eliminates organizational amnesia by maintaining accurate context for all members and agents, functioning as an operational nervous system. It connects to every channel where work happens, meetings, Slack, email, code commits, docs, calendars, and treats them not as artifacts to search, but as living signals to synthesize. The fleeting and the permanent, unified into a memory that understands. The founding team is built for this: - Jae Gwan Park (CEO): Product-first founder, memory systems research at UofT and MIT - Ashwin Gopinath (CSO): Former MIT professor, created "Reflexion" (NeurIPS 2023), agents that learn from mistakes, 2x founder - Andrey Starenky (CTO): Early Vapi engineer, ex-IBM, built to process enterprise-scale data firehose Together is an operator-led fund. We invest in problems we've lived. This is one of them. Many congrats Jae, Ashwin and Andrey, we are so excited to partner with you! Read the full thesis: https://lnkd.in/gixj9cE4 Book a demo: https://www.sentra.app/ #OrganizationalMemory #AI #Sentra #TogetherFund #a16z #ContextGraphs
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Peter OBrien
Digital Finance HQ • 4K followers
Every hire, product feature, and GTM experiment is a capital allocation decision, most teams just don’t call it that. I’m kicking off a 3-part series on capital allocation for founders, operators, and finance leaders with a simple question: ➡️ Will the next $1 you deploy become worth more than $1? Series overview Part 1: defines the core concept + the math Part 2: where capital goes + how to measure whether it’s working Part 3: AIMS framework for communicating allocation decisions to management teams and your board Part 1 (attached here) lays the practical foundation: 🔹 The $1 invested test and ROIIC vs. hurdle rates (scoreboard vs. decision lens) 🔹 A lightweight “investment brief” to evaluate bets (GROW / BUILD / BUY) 🔹 The small metric toolkit that translates finance into operating decisions (NPV / payback / ROIIC / incremental margin) 🔹 Early-stage proxies when DCF inputs are unknowable (burn multiple + revenue quality) 🔹 Operator “vital signs” to spot drift early (profit engine, leverage, cash conversion, optics) Series Roadmap ✔️ This series (Parts 1–3): breadth-first. shared, lightweight framework to define value creation, choose decision-grade metrics, and communicate tradeoffs clearly ✔️ Next series: depth-first. momentum drivers + operational decisions that need near real-time measurement to spot drift early and course-correct fast Read Part 1 here and Part 2 and 3 on substack. Next Series will be out next week. 💰 What’s one bet you’re funding right now, and how will you prove it’s working?
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Matt Wachter
Barber National Institute • 4K followers
I’m lucky to work alongside colleagues like Richard Fruehauf, who constantly push my thinking. His latest piece unpacks why U.S. robotics and drone manufacturing faces uphill economics, and how public policy can help turn the tide. One key takeaway: 232 tariffs on robotics imports could help reset the economics that are holding back U.S. investment and production. It’s a sharp perspective on how policy can shape the future of advanced tech here at home. Well worth a read: https://lnkd.in/edMPTQPQ Richard Fruehauf, Robert J. Szczerba, Michael Lutzky, Edward Ovando, Karl Sanchack, Herman Herman, Jeff Legault, Phil English, Richard Fruehauf, Ryan Aument, Michael Guido, Sheila Fitzgerald Sterrett, David McCormick
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Tony Corbin
White Star Capital • 3K followers
I’m thrilled to share that White Star Capital is backing AMI - Advanced Machine Intelligence in their historic $1.03bn seed round 🚀 - Led by the legendary Yann LeCun and Alex LeBrun. AMI isn't building another LLM, they're building World Models. Why this matters: *Beyond Text: Grounded in JEPA architecture to solve physical-world problems. *Global Powerhouse: A dream team from Meta FAIR, OpenAI, and DeepMind. *Sovereign Tech: A credible European-led alternative to US Big Tech. Excited to be part of this journey along with the rest of the WSC team Eric Martineau-Fortin, Matthieu Lattes, Bérénice Moustial and Victoria Pozzi Rocco Belforti. 🌍✨ https://lnkd.in/eiCKZKSQ #VentureCapital #AI
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Sadhika Agarwal
Equirus • 12K followers
Thrilled to announce our investment in CtrlB! Privilege partnering with founders like Adarsh, who are deeply obsessed with the problem they’re solving - a true force of nature. CtrlB is redefining enterprise observability, building a next-gen telemetry engine that makes search up to 10x faster and 90% cheaper. In an era where enterprises generate terabytes of data every day, CtrlB is closing the gap with a fundamentally new approach to ingesting, indexing, and querying petabyte-scale data - enabling teams to gain real-time visibility without trade-offs between cost and speed. #funding #startups
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Emery Waddell
Vocap Investment Partners • 4K followers
Pumped to double down on the overlooked software founders who have their head down delivering the future in their industries—especially those tired of choosing between bootstrapping or taking excessive VC $$ with boom or boost expectations. Onward!
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5 Comments -
Jordan Steiner, CFA
Developer Capital • 3K followers
"Build the event you wish existed" That's what we at Monadical did last week at #NYTW. We wanted an AI Engineers discussion for Engineers. There's always a lot of events out there for VCs to network, or for startups to learn about G2M, but very little on lessons learned from actual engineers in the field. So that's the event we hosted. Big thank yous to our awesome panel, Roy Pereira, Ben Cohen and Corey J. Gallon. Here's the key takeaways and the AI tools we're using. 🚀 All three panelists independently called AI Agents the most transformative LLM application they’ve used. They specifically called out Claude 3.5 Sonnet for its accuracy and reliability. 🪨 We dug into how LLMs are “jagged”, not general. They can be shockingly good at some tasks and completely fail at others. Everyone agreed: good evaluations are critical (and hard.) 🧪 Corey noted how public benchmarks and reality are two different things. Most public evals are saturated or gamed. ♊ Ben emphasized that AI projects are actually two projects: building the tool and building the evaluation process. 🧱 We explored how falling dev costs may impact startup defensibility and labor demand. Roy shared that founders are already shifting strategies in response. ⚒️ In a world of daily AI launches, the panel discussed how they decide what’s worth attention, and what’s just noise. They called out tools like Goose, Aider, Claude Code, and Monadical’s own Cubbi, which helps run agentic workflows safely in dev environments. (links in the comments). CTA: What would you want to hear in an AI Applied Engineering talk you attended?
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Chris Gonzales
Pro Partner Capital • 10K followers
Summary: The venture firm CRV has raised $750 million for its 20th flagship fund, which will focus on investing in early-stage startups, particularly in the consumer and devtools sectors. Key takeaways: CRV's new fund is smaller than their previous one, but still received strong demand from investors. The firm has a history of successful investments, with 80 startups eventually going public since its founding in 1970. CRV is shifting its focus away from late-stage rounds, citing lower overall returns, and towards seed and Series A investments. Counter arguments: Some may argue that CRV's decision to not raise another late-stage fund could limit its opportunities for growth in the future. The success of the new fund will ultimately depend on the performance of the startups it invests in, which can be unpredictable in the volatile tech industry. #venturecapital #fundraising #startups https://lnkd.in/g8d-N9jX
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Dror Nahumi
Norwest Venture Partners • 8K followers
From the beginning, we believed Lumana was building much more than a smarter surveillance tool. Lumana's platform reflects the next evolution in video intelligence — physical AI. This approach enables systems to go beyond basic detection capabilities to understanding context, infer intent, and deliver real-time insights that improve safety and operations at scale. Further, we decided to take the longer and more difficult direction of building a whole new generation and fully featured Video Management System (VMS). With the company’s $40M Series A, led by our friend Peter Wagner from Wing Venture Capital and our seed partners from SCAPITALVC, we’re doubling down on a platform that’s already proving its value in the real world. We are serving now close to ten thousands enterprise cameras in production! Founders like Sagi Ben Moshe bring a rare mix of vision and execution to the table. From our earliest conversations as an EIR at Norwest, it was clear that Lumana had the potential to reshape how organizations use video. Congratulations to the team on this well-deserved milestone. https://lnkd.in/gwHdaGPZ
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Jeff Immelt
New Enterprise Associates… • 566K followers
Dayna Grayson is a leading VC who has “sat in every chair” at a young age. She founded Construct Capital with Rachel Holt, an early leader at Uber. Together, they are tackling the digitization of industry. Dayna will discuss macro trends, what it takes to be a founder, and the potential for AI. She is one of the few who have successfully blended a career of operations and investing. Check out our discussion at: https://lnkd.in/eYBUGjbW #leadershipdevelopment
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9 Comments -
Harshul Sanghi
4K followers
Great conversations at our WillowTree Ventures dinner with leaders across fintech and AI. A few themes stood out strongly: enterprises are leaning into AI for real efficiency gains, product and engineering orgs still set the agenda, and the whitespace in “boring” industries is wider than most people assume. It’s clear that the next breakout companies in AI for financial services won’t come from the obvious places. Thanks to everyone who joined - excited to keep working alongside founders building in these non-obvious, high-impact wedges.
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Amber Illig
The Council • 5K followers
What kind of mindset does it take to go from building data systems at Palantir, to leading engineering at Komodo Health, to becoming CEO of Particle Health – and suing one of healthcare’s largest incumbents? Jason Prestinario is a First Builder through and through. As CEO of Particle Health, his mission is to fix patient data interoperability, so your primary care doctor, specialist, and surgeon can all make decisions using the same complete health record. What a concept, right? And yet, it’s far from reality. That’s why Jason and the team at Particle are now suing Epic, one of the industry’s largest incumbents, to push for real change. We talked about how he approaches challenges of this scale, and what keeps him grounded in the process. We sat down with Jason to talk about this and much more. Hope you'll enjoy this spicy and insightful episode! Link in comments 🌶️ 👇
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Clay Fisher
Spark Capital • 2K followers
Much of the money and time in healthcare happens past the point of diagnosis. The money: $200B of spend on specialty drugs. The time: putting patients on therapies requires clinical judgment, and navigating a labyrinth of paperwork and people. The result is a byzantine status quo where patients get life saving therapies denied or delayed, and hospital systems capture only $80B of the $200B of drug spend that they originate. Latent’s groundbreaking clinical AI is a portal into the future. Patients get therapies quickly with personalized care, and hospitals transform their bottom line. As a result, Latent has seen extraordinary traction, working with over 50% of the top 20 U.S. health systems in under a year. Latent is one of the biggest and most strategic opportunities in healthcare, sitting in between providers, payors, patients, and pharma. Spark Capital is delighted to support Rishabh Jain and Sriram Somasundaram and this consequential company and to work with Sarah Guo and Michael Dixon.
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Hugo Fdez.-Mardomingo
Acurio Ventures • 5K followers
🦄 $150M to improve tutoring and education globally. Preply just announced a new round, putting the company on a clear trajectory to become an iconic global marketplace. In a world obsessed with fast wins and volatile growth, some companies quietly beat their goals year after year — for more than 6 years in this case (as long as we’ve at Acurio Ventures been partners). A few learnings from this journey, relevant for founders and investors: Pick a growing market with an unsolved problem. 2 out of 8 billion people globally are learning a second language. Despite many options, outcomes are still poor. Our original thesis was simple: if you build the reference platform, everyone who wants to learn will eventually come to you. Category leadership matters. When we backed Kirill Bigai and Dmytro Voloshyn back in 2019 (together with Rob Kniaz), there were dozens of similar startups. Small details showed Preply had already built a superior tutor base and a scalable growth engine. Build a product customers love. Speaking a language and teaching it are very different things. Preply transformed the learning experience by combining a motivated base of +100,000 tutors with tools that actually drive outcomes. Never stop experimenting. Few companies maintain a strong experimentation culture as they scale. Preply’s DNA reminded me of Booking.com — enabling them to execute 10x better than most marketplaces. Great companies turn every change into an opportunity. From riding the post-COVID shift to online learning, to betting early and heavily on AI as Dmytro Voloshyn has excelled at. What once sounded like sci-fi is now reality. Great companies become talent magnets A company maturity can't be addressed only by looking at the revenue, profit or product. I like to see how much better they become at attracting talent and retaining it. Proud that Acurio Ventures made this possible and the WestCap team saw things as bullish as we do and are now supporting the next phase of Preply’s journey. Huge congratulations to the entire Preply team!!
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Martyn Eeles
Clarma Capital • 12K followers
HealthVC x Lusha: Unlocking Smarter Fundraising and Sales Workflows We’re thrilled to announce our newest partnership: HealthVC has teamed up with Lusha to bring next-gen data and prospecting tools to founders, fund managers, and operators across our community. Lusha recently launched a powerful suite of AI-powered features that redefine how go-to-market teams research, prospect, and convert. Now those capabilities are coming to HealthVC Pro subscribers. ✨ With this partnership, you’ll be able to: Surface real-time, accurate, and compliant B2B contact data Use AI Prospecting Chat to instantly uncover new investor or customer leads Tap into CRM-triggered recommendations to stay one step ahead Turn insight into action with Sales Streaming, Lusha’s smarter, connected selling framework. But Lusha’s superpower isn’t just the AI; it’s that the AI sits on top of best-in-class data. That means every signal, every recommendation, and every lead is not just fast, it’s trustworthy. At HealthVC, we’re building more than a newsletter; we’re building the operating system for venture, and this partnership helps our members move faster, pitch smarter, and close better. Available now to all HealthVC subscribers, link in comments.
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Somesh Dash
11K followers
The best founders don’t just build products; they reframe the problem. Ryan Alshak has done exactly that with Laurel - turning time from a background task into a source of insight, alignment, and leverage. IVP is leading Laurel's Series C to help build the system of record for how work actually happens. Read more from Allie Garfinkle: https://lnkd.in/gweNiwsc
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