We’re excited to be at SOT 2026! This year, we are showcasing our Predictive Toxicology capabilities as part of the Computational Toxicology and Drug Discovery specialty sections. We’ll demonstrate how physics-based FEP methods can predict both off-target binding affinity (Kd) and atomistic holo-complex structures – allowing researchers to rationally design out toxicities while maintaining primary efficacy. Stop by our posters to see how Schrödinger is bringing a new level of predictive power to off-target de-risking. #2026SOT #ToxExpo #Toxicology #DrugDiscovery #FEP
Schrödinger at SOT 2026: Predictive Toxicology Capabilities
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Great to see the continued momentum around NAMs at the Society of Toxicology Annual Meeting and ToxExp. FNIH Vice President Stacey Adam, PhD, was grateful for the opportunity to join a special session hosted by JRF Global. These conversations around NAMs and next-gen approaches are critical to foster more human-relevant science that leads to real-world impact. Learn more about what the FNIH is doing in this space: https://lnkd.in/esipAbrg
A week full of science, conversations, and new perspectives at SOT 2026. From presenting our work through poster sessions to being part of engaging discussions on New Approach Methodologies (NAMs), every interaction brought fresh insights and meaningful exchanges. It was great to see the momentum around evolving approaches in toxicology and the shared focus on advancing scientific practices. We had the opportunity to connect with peers, exchange ideas, and discuss how JRF can contribute to supporting research and testing needs in this dynamic landscape. Looking forward to building on these conversations ahead. #SOT2026 #Toxicology #NAMs #ScientificExchange #Collaboration #JRFGlobal
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Translational NAMs are steadily moving from concept to real-world application, bringing new possibilities in toxicology. A session scheduled for 24th March 2026 (1:45–2:45 PM, Room 23C) at the Society of Toxicology Annual Meeting (#SOT 2026 ) will explore their evolution, current landscape, and key challenges ahead. Dr. Abhay Deshpande will be sharing insights on the journey of NAMs, along with important considerations around regulatory clarity and standardisation. The discussion will also highlight JRF Global’s experience in ring validation studies, including key learnings and contributions. We look forward to your active contribution to these discussions, which will be moderated by Clive Roper BSc PhD CBiol CSci ERT FRSB. 👉 Click the link below to get full details about the session: https://lnkd.in/diAwK_-f #SOT2026 #NAMs #TranslationalScience #Toxicology #JRFGlobal #ScientificCollaboration #RegulatoryScience #LifeSciences #Research #Innovation #RiskAssessment #SafetyAssessment #FNIH-VQN, #RoperClive #CRO
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Final day at Society of Toxicology (SOT). After a full week of conversations, one thing is clear: The core challenge in nonclinical is not scientific. It is structural. Data is captured in one system. Analysis happens in another. Reporting is assembled manually. And the connections between them are fragile. This shows up everywhere: • pharma • CROs • biotech The industry has adapted to this model. But it does not scale. The opportunity is to move from stitched workflows to a single, connected system. That is the direction we’re building toward with #TurboPlatform. We’ll carry these conversations forward after SOT. If we didn’t connect this week, happy to continue the discussion. #2026SOT #ToxExpo #Toxicology
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Proud to share that we announced Resero Analytics’ new platform at SOT — designed for capturing, analyzing, and reporting nonclinical data, with support for bioanalysis and PK/TK. At the heart of this platform is a simple idea: powerful technology should feel intuitive. We focused on delivering a simplified user experience while advancing innovation in ways that matter to scientific teams. I’m especially proud because this was built by a small but highly motivated team. It’s proof that with the right tools, clear vision, and a determined group of people, you really can move mountains. This is just the beginning. More to come, and stay tuned.
Final day at Society of Toxicology (SOT). After a full week of conversations, one thing is clear: The core challenge in nonclinical is not scientific. It is structural. Data is captured in one system. Analysis happens in another. Reporting is assembled manually. And the connections between them are fragile. This shows up everywhere: • pharma • CROs • biotech The industry has adapted to this model. But it does not scale. The opportunity is to move from stitched workflows to a single, connected system. That is the direction we’re building toward with #TurboPlatform. We’ll carry these conversations forward after SOT. If we didn’t connect this week, happy to continue the discussion. #2026SOT #ToxExpo #Toxicology
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One message stood out at the Society of Toxicology (SOT) annual meeting, NAMs are transforming toxicology. But strong NAMs rely on strong biology: in vitro assay systems like HepaRG®, bring the metabolic competence and human relevance needed to make these approaches truly predictive: From mechanism to decision. Thank you to everyone we connected with in San Diego and a big thank you to the organizers of this meeting. #NAMs #Toxicology #InVitroModels #HepaRG #DILI #ADME #Biopredic
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Expanding our alternative testing capabilities With the addition of the in vitro eye irritation method (OECD 492B) and the phototoxicity model (OECD 498), Toxi-Coop now provides fast, reliable, and fully compliant testing solutions to support cosmetic product authorization. These internationally validated alternative methods help our partners generate high-quality data while supporting modern, animal-reduction testing strategies. 📍 Meet our team and learn more at Society of Toxicology (SOT) 2026 ToxExpo, San Diego, Booth #1739, March 22–25. #ToxiCoop #Cosmetics #OECD #InVitroTesting #Toxicology #AlternativeMethods #SOT2026
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In vitro toxicology isn’t just an early screen anymore—evolving industry thinking and innovative regulatory expectations have made sure of that! Instead, in vitro toxicology is becoming a core lever for making faster, more confident safety decisions with more human-relevant data. This post serves as a 5-step playbook for how sponsors can use in vitro toxicology to catch risk earlier, reduce late-stage surprises, and build a clearer safety story across development. https://hubs.li/Q042N6Bp0 #drugdevelopment #toxicology #invitro #preclinical #IND #3Rs #NAMs #riskassessment
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In vitro toxicology isn’t just an early screen anymore—evolving industry thinking and innovative regulatory expectations have made sure of that! Instead, in vitro toxicology is becoming a core lever for making faster, more confident safety decisions with more human-relevant data. This post serves as a 5-step playbook for how sponsors can use in vitro toxicology to catch risk earlier, reduce late-stage surprises, and build a clearer safety story across development. https://hubs.li/Q042N69c0 #drugdevelopment #toxicology #invitro #preclinical #IND #3Rs #NAMs #riskassessment
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Rethinking human safety assessments—with science that’s built for the future New Approach Methods (NAMs) are transforming toxicology and safety testing by delivering more human‑relevant data, improving efficiency, and reducing reliance on traditional models. This guide breaks down how NAMs are being used today—and why they’re becoming essential to modern safety assessments. Read the guide: https://lnkd.in/g5uxjM5p #HumanSafety #Toxicology #NewApproachMethods #DrugDevelopment #ScientificInnovation
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Rethinking human safety assessments—with science that’s built for the future New Approach Methods (NAMs) are transforming toxicology and safety testing by delivering more human‑relevant data, improving efficiency, and reducing reliance on traditional models. This guide breaks down how NAMs are being used today—and why they’re becoming essential to modern safety assessments. Read the guide: https://lnkd.in/guRSPsDy #HumanSafety #Toxicology #NewApproachMethods #DrugDevelopment #ScientificInnovation
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