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• Led the discovery and preclinical advancement of two radiopharmaceutical…
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Guangcheng Jiang posted thisExcited to share that I’ll be presenting two posters at SNMMI 2025 in New Orleans (June 21-24)! 1️⃣ FL-261: A theranostic RDC vector for c-MET-positive cancers (#251656) 2️⃣ [⁶⁸Ga]Ga/[²²⁵Ac]Ac-FL-031: A theranostic pair targeting SSTR2-positive cancers (#251518) Looking forward to connecting and sharing our latest work in radiotheranostics! #SNMMI2025 #Theranostics #Radiopharmaceuticals #NuclearMedicine #cMET #SSTR2
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Guangcheng Jiang reposted thisGuangcheng Jiang reposted thisFull-Life Technologies announced it has received clearance of its Investigational New Drug (IND) Application from the U.S. Food and Drug Administration (FDA) for clinical trials of ²²⁵Ac-FL-020, its PSMA-targeted radiopharmaceutical for the treatment of metastatic castration-resistant prostate cancer (mCRPC). #FullLife #FDA #IND #Ac225 #mCRPC #radiopharmaceuticalsFull-Life Technologies Announces Clearance from FDA of IND Application for ²²⁵Ac-FL-020 for the Treatment of Metastatic Castration-Resistant ProstateFull-Life Technologies Announces Clearance from FDA of IND Application for ²²⁵Ac-FL-020 for the Treatment of Metastatic Castration-Resistant Prostate
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Guangcheng Jiang liked thisGuangcheng Jiang liked thisLooking back over 46 years, the chapters are clear. Youthful innocence. Coming of age. The college party. The vampire hours. The elevator down. Then the long, unglamorous work of putting Humpty Dumpty back together. — September 18th, 2002. I was 23, relapsing for a third time – this time with over a year of sobriety behind me. So I went into plain-sight hiding. Drinking by myself, during shifts, between shifts, and around the clock until I passed out. Two weeks in and seemingly no end in sight, my buddy Justin spotted me across that grungy Pier Ave bar. I cowered like a dog in shame, could barely make eye contact as he dragged me out of there, threw me in his car, and delivered me to my parents' doorstep for the final time. Next morning (~noon, still in bed), Mom hands me the phone with a new hardcore sponsor on the line. “Tim – meet me at my office in 1 hour”. Tough love and getting kicked to the curb was just around the corner for me, along with the realization that this was my last last chance. No money. No degree. No enablers left. Unemployable. Amends unmade. Totally depressed and non-functional. The gift of desperation had finally arrived. — I never went to grad school. But what I learned in my early 20s – through lived experience, not textbooks – didn't stay in "recovery world." It came with me when I eventually re-enrolled at UCSD to finish my undergrad. It came with me through 20+ years of finally adulting as an employee, spouse, son, father, & friend. It taught me how to live life on life's terms – and find some degree of happiness there, regardless of external circumstance. No cure. No magic pill. No arrival. Just the systematic doing of tiny things, consistently over time, often contrary to how I felt at the time. Plan to share more of these – stories connecting sobriety, leadership, relationships, lessons from nature, and the daily work of getting into action. Take what's useful. (pic from a few years ago standing under the SunGod @ UC San Diego 🧜♂️)
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Guangcheng Jiang liked thisGuangcheng Jiang liked thisExcited to share that TippingPoint Biosciences (https://lnkd.in/gUJrDeek) just successfully closed an overscribed seed round and brought the total raise to 7 million dollars to date (https://lnkd.in/gVhNUiQu). Big shout-out to our prestigious investors-SOSV and LKS Fund (coleads), Sazze Partners, FreeFlow Ventures, StoryHouse Ventures, Sontag Innovation Fund, BrightEdge - American Cancer Society, XEIA Venture Partners and WeCAN, for having a LONG view and supporting NOVEL biology and platform. TippingPoint was co-founded by Laura Hsieh, PhD and renowned University of California, San Francisco biologist Geeta Narlikar PhD (member of the National Academy of Sciences and a AAAS). I have been advising Laura and Geeta and other members of the team for the past two years and witnessed how the team conducted great science very diligently and efficiently. I am looking forward to continuing helping the team accomplish more greatness in the next phase of growth.
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Guangcheng Jiang liked thisIt's been an incredible journey to take a scientific concept from discovery to human trials and now this transition. I could not be more proud of the team that has made this moment a reality. Excited doesn't even begin to describe the feeling of having a partner with the knowledge, vision and resources to bring this to the many patients that will benefit from Exl-111. #Excellergy #Novartis #Allergy #CSUGuangcheng Jiang liked thisNovartis has agreed to acquire Excellergy, Inc., a private clinical-stage biotechnology company developing next-generation anti-IgE therapies for IgE-driven diseases. Excellergy’s lead asset, Exl-111, is a Phase 1, half-life extended and high-affinity anti-IgE antibody designed to dissociate receptor-bound IgE, with the potential to deliver faster and deeper suppression of IgE signaling than current anti-IgE approaches. In simple terms, it is designed to go beyond conventional anti-IgE therapy and could help improve symptom control for patients across a range of allergic diseases. The proposed acquisition also builds on deep Novartis expertise in IgE biology and strengthens the immunology pipeline, especially in the food allergy space. For more information: https://lnkd.in/gHaPPCu6
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Guangcheng Jiang liked thisGuangcheng Jiang liked thisWatching my daughters grow up (too fast!) and looking around at the powerful women in my life, can’t help but think of how they model leadership qualities this world so desperately needs. Resilience. Patience. Restraint. Emotional intelligence & the ability to carry strength and softness in the same breath. Mom raised three boys (dad too, if we’re being honest), pulled me out of a dark spiral in my 20’s, and remains the person everyone turns to for advice born not out of logic but from empathy, wisdom, and all those “soft” qualities that are anything but. And my wife Monique - leading the charge as a high school PE teacher in a male‑dominated environment - carrying the perfect balance of tough & tender love as mom & “Coach Swift” to our oldest daughter Sophia. When we finally & fully hand over the reins to women, it’s hard not to imagine a healthier, more caring, more functional society. A couple of days ago Sophia texted me: “Dad, I won the scholarship” and included the essay she wrote. Solid writing aside, it was the awareness & ownership of growth from a 16 yr old that floored me (yes, girls are light years ahead of boys at that age 😉) “Lessons in Calculus, Chemistry, & Computer Science have taught me their intricacies and challenges; History textbooks have informed me of plights and mistakes of the past, and each year I am plunged further into the minutia of the English language and each rule that some word dares to contradict. Despite the academic value, it pales in comparison to what I learned through sports this past year.” She goes on to talk about going out for pole vaulting and struggling to clear the opening height (7ft) those first few comp’s. So she doubled down. Found an elite club 15 minutes away, trained twice a week on top of regular practice, pushing through 3hr conditioning sessions & the kind of “sometimes miserable” work that tests you physically & mentally. “Hard work, passion, & showing up became the lesson” according to Fifi. Watching kids take on new things, fall, get up, & try again is a reminder of how we adults slowly lose the courage to be beginners. We cling to comfort. We don’t want to suck or “fail” (🙋🏻♂️), so we stand on the sidelines… & unfortunately stop growing. An old sponsor used to remind me: “Willingness without action is fantasy.” Akin to not having have to *DO* anything to possess talent, you’re just born with it. Struggle, effort, perseverance… those are the qualities that define a person. Now in her sophomore year, Sophia’s vaulting 10ft and balancing AP classes, 4 to 6 practices a week, ASB / Dance Commitee leadership, & tutoring 8th grade girls in math before school. Her dream is to attend UCLA or Stanford on a sports scholarship and become a surgeon because of the care she received from doctors at age 5 for a rattlesnake bite. To the mothers, daughters, wives, & all the amazing women I’m fortunate to work alongside - THANK YOU for all you do. #InternationalWomensDay
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Guangcheng Jiang liked thisGuangcheng Jiang liked thisThe FDA just made a move that could fundamentally change the treatment of plaque psoriasis. Yesterday, March 18, 2026, Icotrokinra (ICOTYDE™) was officially approved. Historically, if you wanted to target the IL-23 pathway with high precision, you needed an injectable biologic (like Tremfya or Skyrizi). Small molecule orals, while convenient, often struggle to match that specific "biologic-level" efficacy. Icotrokinra changes that by being a cyclic peptide. It’s small enough to be taken as a once-daily pill but precise enough to selectively block the IL-23 receptor with picomolar affinity. Beyond psoriasis, J&J is already pushing this molecule into Phase III for Ulcerative Colitis and Psoriatic Arthritis. We are witnessing a shift where the "biologic vs. oral" gap is finally closing. For those of us in the lab and the industry, this is a masterclass in peptide engineering—turning a complex protein-protein interaction into a stable, bioavailable oral dosage form.
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Guangcheng Jiang liked thisGuangcheng Jiang liked thisThe most anticipated meeting in “America’s Finest City”. Look forward to connecting, reconnecting, catching up, running into…. Got invited to a special long-term member event- which reminds me that this is my 25th year being an #AACR member! When I first joined AACR in 2000, I was only a 2nd year graduate student- time’s flying and a lot of (good) things have happened since then. Also taking home court advantage, I am participating in the special programs for high school students, hoping to help inspire our next generation of scientists and physicians. Will be fun!
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Guangcheng Jiang liked thisGuangcheng Jiang liked thisWeathered and bruised, but never beaten. Nothing entitled, everything earned. I am always captivated by the dramatic, rugged, and harsh scenery of the frontier lands. A strong sense of time, space, endurance, hope
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Guangcheng Jiang liked thisGuangcheng Jiang liked thisJoin me at the LSX Investival Showcase USA, March 10-11, in Miami, where visionary life-science innovators secure game-changing capital and partnerships. Register here: https://lnkd.in/eYDVSaUZ #investival #biotechnology #biopharma #medicaldevices #digitalhealth
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